|Place of Origin:||China|
|Model Number:||Vitamin B9 Folic Acid|
|Minimum Order Quantity:||Negotiation|
|Packaging Details:||Aluminum Foil Bag, barrel, or drum.|
|Delivery Time:||7-15 working days|
|Payment Terms:||T/T, western union, moneygram|
|Supply Ability:||5 - 25 metric ton per month|
|Other Names:||Folic Acid/Vitamin B9||Appearance:||Pills, Powder, Tablets|
|Application:||Nutrition Supplement||Cas No.:||59-30-3|
|Mf:||C19H19N7O6||Shelf Life:||2 Years|
|Melting Point:||250 °C||Density:||1.4704|
vitamin c supplement tablet,
Folic acid is an important B-group water-soluble vitamin, which was isolated from spinach in 1941. It is named after the rich content of green leaves, also known as pteroylglutamic acid. There are several forms in nature, and the parent compound is composed of three components: pteridine, p-aminobenzoic acid and glutamic acid. Folic acid contains one or more glutamyl groups. Most of the naturally occurring folic acid is in the form of polyglutamic acid. The bioactive form of folic acid is tetrahydrofolate. In 1981, folate and related compounds with biological activity of folate were called fo lacin by cnain. Biological activity is generally expressed in weight units. Folic acid is a kind of dark yellow substance, which is not easy to dissolve in water, and its sodium salt has high solubility. It is stable to heat in neutral and alkaline solution, but decomposes when the temperature exceeds 100 ℃ in acid solution. Folic acid and its sodium salt are destroyed by light in solution.
Folic acid isolated from liver and yeast mainly contains three glutamate or seven glutamate derivatives.
Most of the folate in the diet is polyglutamic acid compound, which can not be completely absorbed into the blood. In the experiment, the second glutamic acid residue was labeled with 14C, and it was decomposed into butterfly glutamic acid during absorption. There was no radioactive folate in serum, but 14C in exhaled gas. The decomposition of polyglutamic acid chain was carried out in intestinal mucosal cells. Folic acid is stored in small amounts in the liver. The 4-hydroxy group in the nucleus of pteridine is replaced by 4-hydroxy group to form 4-aminofolate, which is an antagonist of folate and hinders the synthesis of nucleic acid. There are two ways of active absorption and diffusion passive absorption of folate in vivo. The absorption site is mainly in the upper part of small intestine. The higher the absorption rate of reduced folate, the lower the absorption rate of glutamyl, and the higher the absorption rate of glucose and vitamin C. The absorbed folate is stored in intestinal wall, liver, bone marrow and other tissues in vivo. It is reduced to tetrahydrofolate (THFA or fh4) with physiological activity by folate reductase with the participation of NADPH, which is involved in the synthesis of purine and pyrimidine. Therefore, folic acid plays an important role in protein synthesis, cell division and growth, and promotes the formation of normal red blood cells. When lacking, it can reduce the production of hemoglobin in red blood cells and block the maturation of cells, leading to megaloblastic anemia. Human intestinal bacteria can synthesize folate, so it is not easy to lack it. When malabsorption, metabolic disorder or long-term use of intestinal antibacterial drugs, it can cause folic acid deficiency. In addition, folate is also widely found in animal and plant foods, which are rich in viscera, eggs, fish, pears, broad beans, beets, spinach, cauliflower, celery, lettuce, citrus, nuts and pulses. When the daily intake of folic acid is maintained at 3.1 μ g / kg, the body can have a proper amount of folic acid reserve; the total daily intake of folic acid of pregnant women should be more than 350 μ g; the safe intake of infants is similar to that of adults by kg weight, that is, 3.6 μ g / kg can meet the needs of growth and maintenance of normal blood picture.
Folic acid is used for preventing and treating low blood levels of folate (folate deficiency), as well as its complications, including “tired blood” (anemia) and the inability of the bowel to absorb nutrients properly. Folic acid is also used for other conditions commonly associated with folate deficiency, including ulcerative colitis, liver disease, alcoholism, and kidney dialysis.
Q1: How long is your delivery time?
A: Prompt shipment after receipt of order confirmation for regular products. Generally it is 1-5 days if the goods are in stock. or it is 5-15 days if the goods are not in stock, it is according to quantity.
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