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Thiamphenicol 15318-45-3 Antibiotic Powder Pharmaceutical Raw Material

Thiamphenicol 15318-45-3 Antibiotic Powder Pharmaceutical Raw Material

    • Thiamphenicol 15318-45-3 Antibiotic Powder Pharmaceutical Raw Material
    • Thiamphenicol 15318-45-3 Antibiotic Powder Pharmaceutical Raw Material
  • Thiamphenicol 15318-45-3 Antibiotic Powder Pharmaceutical Raw Material

    Product Details:

    Place of Origin: China
    Brand Name: Leji
    Model Number: Thiamphenicol

    Payment & Shipping Terms:

    Minimum Order Quantity: Negotiation
    Price: Negotiation
    Packaging Details: Aluminum Foil Bag, barrel, or drum.
    Delivery Time: 7-15 working days
    Payment Terms: T/T, western union, moneygram
    Supply Ability: 5 - 25 metric ton per month
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    Detailed Product Description
    Type: Antibiotic Medicine Mf: C12H15Cl2NO5S
    Cas No.: 15318-45-3 Melting Point: 163-166 °C
    Shelf Life: 2 Years Water Solubility: Soluble In Water
    Density: 1.3281 Color: White To Off-white
    High Light:

    doxycycline hyclate

    ,

    chlortetracycline powder

    Thiamphenicol 15318-45-3 Antibiotic Powder Pharmaceutical Raw Material

     

    Description

         Methamphenicol is a broad-spectrum chloramphenicol antibiotic, which has a stronger effect on Gram-negative bacteria than that on positive ones. Under normal temperature, it is white to almost white crystalline powder or crystal, which can be absorbed rapidly and completely by oral administration. In terms of metabolism, it is mainly excreted from urine in prototype. Clinically, it is mainly used for the treatment of respiratory, urinary, hepatobiliary, typhoid and other intestinal surgery, gynecology and obstetrics, and facial infections, especially for mild and moderate infections. Its chemical structure is similar to that of chloramphenicol. Its methylsulfone group replaces the nitro group of chloramphenicol, so its toxicity is 2.5-5 times higher than that of chloramphenicol. It has a strong antibacterial effect on Gram-positive bacteria such as pneumococcus and hemolytic streptococcus. It also has a strong antibacterial effect on Gram-positive bacteria such as gonococcus, meningococci, pulmonary bacilli, Escherichia coli, Vibrio cholerae, dysentery bacteria and influenza bacteria. It also has a certain antibacterial effect on anaerobic bacilli, Rickettsia, amoeba, etc. Its mechanism of action and chloromyces Same element. It is mainly to inhibit the synthesis of bacterial protein. The drug can be absorbed rapidly by oral administration, and the blood concentration can reach the peak within 2 hours, with a half-life of 5 hours, which is longer than chloramphenicol. The bacteria have complete cross resistance between the product and chloramphenicol, and partial cross resistance between the product and tetracycline.
         Methamphenicol also has strong immunosuppressive effect and is an excellent immunosuppressant. Its mechanism of action is significantly different from other immunosuppressive agents, and its immunosuppressive effect is several times higher than that of chloramphenicol. To reflect the effective prolongation of transplantation and surgical homograft

     

     

    Product Parameters

     

    Item
    Specifications
    Results
    Appearance
    Fine white or yellowish-white crystalline powder or crystals
    Fine white crystalline powder
    Identification
    According to BP2012
    Complies
    Light absorption
    According to BP2012
    Complies
    Acidity or alkalinity
    According to BP2012
    Complies
    m.p
    163~167℃
    165℃
    Specific optical rotation
    -21°~-24°
    -22°
    Chloride
    ≤200ppm
    <200ppm
    Sulphated ash
    ≤0.1%
    0.05%
    Heavy metals
    ≤10ppm
    <10ppm
    Loss on drying
    ≤1.0%
    0.02%
    Assay
    98.0%~100.5%
    99.90%


      Function

     

    Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

    Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.
    Unlike chloramphenicol, thiamphenicol is is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats the drug is excreted both as parent drug and as thiamphenicol glucuronate.

     

    FAQ

     

    Q1: How long is your delivery time?

     

    A: Prompt shipment after receipt of order confirmation for regular products. Generally it is 1-5 days if the goods are in stock. or it is 5-15 days if the goods are not in stock, it is according to quantity.

     
    Q2: How much for the freight?
     
    A: It depends on your area, we will use DHL, FedEx and EMS bulk service, it had discount as normal express service.
     
    Q3: How can i release the payment to you?
     
    A: We can receive your payment by T/T, moneygram or Western union which is recommended.

     

    Contact Details
    Wuxi Leji Biological Technology Co., Ltd

    Contact Person: Max

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