Safe Shipment 1-Phenyl-2-Nitropropene P2np Cas 705-60-2 Yellow Crystalline Powder

1-Phenyl-2-nitropropene,

or simply phenyl-2-nitropropene, or P2NP, as it is commonly referred to, is a chemical compound from the

aromatic group of compounds, with the formula C9H9NO2. It is a light-yellow crystalline solid with a distinct

smell.[6] Phenyl-2-nitropropene is used in the pharmaceutical industry to manufacture the drug Adderall,

an amphetamine mixture used to treat ADHD and narcolepsy. P2NP and other similar nitrostyrenes are also

employed in the clandestine manufacture of drugs of the amphetamine class, and are listed as drug precursors

in many countries.

P2NP Usage:

In the pharmaceutical industry, P2NP is used to produce a racemic amphetamine mixture, branded under the

trade names Adderall and Mydayis, amongst others. In this case, the double bond is hydrogenated and the

nitro group is reduced,[10] thus 1-phenyl-2-nitropropene becomes 1-phenyl-2-aminopropane, which is another

name for amphetamine. Different reducing agents and solvents are used for this reaction, and various protocols

exist. Often lithium aluminium hydride (LAH), aluminum amalgam or Raney nickel are used as a reducing agent,

and the reaction is carried in a solvent like isopropyl alcohol or THF

Safety and Storage:

P2NP is labeled as harmful by the GHS, and is a known irritant. Thus, breathing fumes and direct skin and eye

contact should be avoided. The median lethal dose for oral exposure in rats and mice is greater than 500 mg/kg

and 1176 mg/kg, respectively. Based on available data, the classification criteria are not met to classify P2NP as

a carcinogen. However, the toxicological properties have not been thoroughly investigated.

P2NP should be stored at 2°C to 8°C and away from strong oxidizing agents. At higher temperatures, P2NP is not

very stable, and degrades with time.

Company Profile:

Wuhan Shuokang Biological technology Co., Ltd is an large-scale fine chemical raw material manufacturer

integrating production and sales such as 2,5-Dimethoxybenzaldehyde, clobetasol propionate, 1.3-dihydroxyacetone,

sodium cyanbohydride, 6-mercapto-purine, etc., with a complete and scientific quality management system.

Besides our company pays great attention to environmental protection and operates the factory in full accordance

with the national environmental protection regulations. Over the years, thanks to our high-quality service to customers,

high-quality products, competitive prices and professional talents. Shuokang has developed rapidly and has become

a one-stop buyer and service provider for many customers around the world. The company's integrity, strength and

product quality has been recognized by the industry. In the face of more opportunities and challenges in the futrue,

Shuokang will be more innovative and pragmatic, and make unremitting efforts. Shuokang is willing to cooperate

with colleagues from alll over the world to visit, guide and business negotiation.